oalib

OALib Journal期刊

ISSN: 2333-9721

费用：99美元

投稿

时间不限

( 9 )

( 2673 )

( 2672 )

( 2454 )

自定义范围…

匹配条件： “Ali Akbari Sari” ，找到相关结果约28744条。
列表显示的所有文章，均可免费获取
第1页/共28744条
每页显示 条
A Systematic Review of the Effects of Diffuse Optical Imaging in Breast Diseases
Ali Akbari Sari,Mohammadreza Mobinizadeh,Mahdi Azadbakht
Iranian Journal of Cancer Prevention , 2013,
Abstract: Background: Optical mammography is a new diagnostic method that uses Near-infrared for detection of functional abnormalities and shows tissue activities by measuring absorption and scattering of Near-infrared light. This study aims to evaluate the safety and effectiveness of this technology.Methods: Cochrane Library (Issue 10, 2012) and Medline (Nov 2012) were searched using free text and Mesh. Studies that compared optical mammography with other diagnostic methods and used outcomes such as sensitivity, specificity and safety were included. Results: Twelve studies were included in this review. A multicenter RCT showed that among 875 biopsied lesions, suspicion index led to 97% sensitivity, 14% specificity, 95% negative predictive value and 24% positive predictive value. In terms of oxygenation index, the included studies found that the process should be used with various wavelengths compared to single wavelength technique (690, 750, 788, 856 nm or 683, 912, 975nm). In terms of sensitivity and specificity, Diffuse Optical Tomography Computer Aided Detection is capable of distinguishing healthy tissues from malignant ones with 89% sensitivity and 94% specificity. Also, this technology could show increased blood flow around the tumor tissue compared to the healthy tissue effectively. Included studies did not report any information about the effects of technology on changing the treatment process or the final health outcomes. Conclusion: Optical mammography is a safe, noninvasive, non-ionized diagnostic technology that can be used as a diagnostic supplement alongside conventional mammography for differentiating benign and malignant tumors. Women with higher breast density should be screened at younger ages and with more persistence than those who have lower densities.
Evaluation Efficacy and Safety of Vortioxetine 20 mg/d versus Placebo for Treatment Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials  [PDF]
Masoud Behzadifar, Hamidreza Dehghan, Korush Saki, Meysam Behzadifar, Abouzar Keshavarzi, Maryam Saran, Ali Akbari Sari
Pharmacology & Pharmacy (PP) , 2015, DOI: 10.4236/pp.2015.64024
Abstract: Major depressive disorder, a common debilitating illness, is one of the leading causes of disability and disease worldwide. Different drugs for the treatment of patients with major depression can be used. Vortioxetine for the treatment of major depressive disorder was approved by the Food and Drug Administration (FDA) in 2013. This study aimed to evaluation efficacy and safety Vortioxetine 20 mg/d compared placebo in major depressive disorder. To conduct this study, we searched Pub Med, Cochrane library, Scopus, and Central Register of Controlled Trials. This study by including randomized controlled trials (RCTs) that evaluated this study by including randomized controlled trials (RCTs) that evaluated Vortioxetine 20 mg/d in patients with major depressive disorder. Data analysis was conducted by standard mean different ratios (SMD) with 95% confidence intervals (CIs), P values and odds ratios (ORs) for adverse events with 95% confidence intervals (CIs) and P values; heterogeneity testing and sensitivity analysis was also performed in this study. We found that 4 articles met the inclusion criteria and were finally used for this meta-analysis. Results showed statistical significance in the MADRS (Montgomery-Åsberg Depression Rating Scale), SMD = -4.75 with 95% CI [-6.84, -2.65] and P value < 0.00001), for Clinical Global Impression Scale-Improvement (CGI-I) SMD was -4.34 with 95% CI [-6.41, -2.27] and P value < 0.00001, and for Sheehan Disability Scale (SDS) SMD was -2.62 with 95% CI [-3.99, -1.25] and P value < 0.00001. The pooled analysis for safety demonstrated for diarrhea OR = 0.92 with 95% CI [0.46, 1.83] , P value = 0.09, for dry mouth OR = 1.74 with 95% CI [1.07, 2.83] , P value = 0.80, for dizziness OR = 1.62 with 95% CI [0.72, 3.66] , P value = 0.05, for fatigue OR = 1.17 with 95% CI [0.34, 4.08], P value = 0.07, for headache OR = 1.28 with 95% CI [0.91, 1.79], P value = 0.60 and for nausea OR = 4.78 with 95% CI [3.43, 6.67], P value = 0.61. Vortioxetine 20 mg/d versus placebo showed a significant difference for nausea and dry mouth, but no significant differences were observed for the four adverse effects. In several studies of the drug Vortioxetine 20 mg/d, the treatment of major depressive illness has been more effective for evaluating the effectiveness of this drug, which must be more clinical studies of sound.
Efficacy and Safety of Vortioxetine and Duloxetine 60 mg Compared Placebo for the Treatment of Major Depressive Disorder: A Systematic Review and Meta-Analysis  [PDF]
Masoud Behzadifar, Abouzar Keshavarzi, Abed Tofighian, Mohammad Rastian, Mohammad Zobidi, Ali Akbari Sari
Journal of Behavioral and Brain Science (JBBS) , 2015, DOI: 10.4236/jbbs.2015.510041
Abstract: Background: Major depressive disorder is a serious public health problem affecting the lives of millions in the worldwide and leading causes of disability and disease. This study aimed to evaluate the efficacy and safety of Vortioxetine and Duloxetine 60 mg compared to placebo for the treatment of major depressive disorder. Method: We searched the Cochrane library, Pub Med, CRD, Scopus, and Central Register of Controlled Trials to January 2015. We also searched ClinicalTrials.gov, International depressive disorder Conference and the Anxiety Disorders and Depression Conference. We identified that five randomized clinical trials were ultimately included in a Meta analysis. Data analysis was conducted by Standardized Mean Differences (SMD) for Montgomery-Åsberg Depression Rating Scale (MADRS), and Odds Ratio (OR) for adverse events. The SMD and OR reported by 95% CI. Results: Results showed statistical significance in the MADRS for Vortioxetine (SMD = ﹣3.29; 95% CI ﹣4.47 to ﹣2.10; I2 = 99.3%) and for Duloxetine 60 mg (SMD = ﹣6.35; 95% CI ﹣8.84, ﹣3.87; I2 = 99.3%). Results showed that the Vortioxetine 2.5, 5, 10, 15, 20 mg and overall compared to placebo showed a significance for Nausea and no significance for diarrhea, dry mouth, dizziness, fatigue and headache. Also results of Duloxetine 60 mg showed a significant effect for dry mouth, dizziness, fatigue and nausea. Conclusion: It is necessary to do more studies so as to better assess and much more powerful than the evidence for the use of this drug in the treatment of depression.
The effect of NAFLD (non-alcoholic fatty liver disease) on long-term outcome of chronic hepatitis B in Iranian patients  [PDF]
Arezoo Estakhri, Ali Akbari Sari, Sahar Naz Nedjat, Marym Rohban, Naser Rakhshani, Seyed Mohammad Tavangar, Reza Malekzadeh, Ghodrat Montazeri
Open Journal of Gastroenterology (OJGas) , 2012, DOI: 10.4236/ojgas.2012.21004
Abstract: Background: The influence of Non-Alcoholic Fatty Liver Disease on the outcome of chronic hepatitis B disease, including viral, biochemical and histologic characteristics, in Iranian patients is not yet fully un- derstood. Aim: To evaluate the effect of Non-Alcoholic Fatty Liver Disease (NAFLD) on long-term histology- cal, biochemical and viral outcome of chronic he- pa-tictis B in Iranian patients. Methods: We retro- spec-tively evaluated 94 “e Ag” negative chronic hepatitis B patients (with NAFLD: 44, without NAFLD: 50). Non-Alcoholic Fatty Liver Disease was diagnosed based on liver biopsy according to Kleiner classifica-tion. Liver biopsy was done for all patients. Serologi-cal and biochemical variables were evaluated with repeated measure analysis. Results: Non-Alcoholic Fat- ty Liver Disease (NAFLD) was present in 47% of the patients (44 out of 94 patients). In the NAFLD group, increase in AST, ALT, stage (P = 0.002), grade, and total score of liver biopsy were independently related to non-alcoholic fatty liver disease, while HBV-DNA viral load did not correlate with the presence of a fatty liver. Conclusion: Abnormalities of liver enzymes and liver histopathology are more prevalent in concurrent chronic hepatitis B and Non-Alcoholic Fatty Liver Disease (NAFLD).
Private and social time preference for health outcomes: A general population survey in Iran
Abolghasem Pourreza,Ali Akbari Sari,Alireza Mahboub-Ahari,Maryam Moeeni,Trevor A. Sheldon
- , 2019, DOI: 10.1371/journal.pone.0211545
Abstract:
Factors hindering the adherence to clinical practice guideline for diabetes mellitus in the Palestinian primary healthcare clinics: a qualitative study
Ali Akbari Sari,Amirhossein Takian,Arash Rashidian,Aymen Elsous,Mahmoud Radwan,Sanaa Abou-Dagga
- , 2018, DOI: 10.1136/bmjopen-2017-021195
Abstract: Objective Despite a high number of the internationally produced and implemented clinical guidelines, the adherence with them is still low in healthcare. This study aimed at exploring the perspectives and experiences of senior doctors and nurses towards the barriers of adherence to diabetes guideline. Setting The Palestinian Primary Health Care-Ministry of Health (PHC-MoH) and Primary Health Care-United Nations Relief and Works Agency for Palestine Refugees in the Near East (PHC- UNRWA) in Gaza Strip. Participants Individual face-to-face in-depth interviews were conducted with 20 senior doctors and nurses who were purposefully selected. Methods Qualitative design was employed using the theoretical framework by Cabana et al to develop an interview guide. Semi-structural and audio-recorded interviews were conducted. Data were transcribed verbatim and thematically analysed. Results The key theme barriers identified by participants that emerged from the analysed data were in regard of the PHC-MoH lack reimbursement, lack of resources and lack of the guideline trustworthiness, and in regard of PHC-UNRWA the time constraints and the lack of the guideline trustworthiness. The two key subthemes elicited from the qualitative analysis were the outdated guideline and lack of auditing and feedback. Conclusion The analysis identified a wide range of barriers against the adherence to diabetes guideline within the PHC-MoH and PHC-UNRWA. The environmental-related and guideline-related barriers were the most prominent factors influencing the guideline adherence. Our study can inform the policy makers and senior managers to develop a tailored interventions that can target the elicited barriers through a multifaceted implementation strategy
Automation of Fingerprint Recognition Using OCT Fingerprint Images  [PDF]
Nasibe Akbari, Ali Sadr
Journal of Signal and Information Processing (JSIP) , 2012, DOI: 10.4236/jsip.2012.31015
Abstract: Automated recognition of a person is one of the most critical issues in the modern society. Common biometric systems rely on the surface topography of an object and, thus, are potentially vulnerable for spoofing. Optical coherence tomography is a technology that has the capability to probe the internal structure of multilayered tissues. The paper describes an algorithm for automation fingerprint recognition that the algorithm is applied on the OCT fingerprint images. This algorithm is based on scanning of the enhanced and segmented OCT images.
Study of Oxidation Kinetics in Air of Zircaloy-4 by in Situ X-Ray Diffraction  [PDF]
Noureddine Selmi, Ali Sari
Advances in Materials Physics and Chemistry (AMPC) , 2013, DOI: 10.4236/ampc.2013.32023
Abstract:

The zircaloy-4 is an alloy of zirconium, which has a very weak thermal neutron absorption, satisfactory mechanical properties and good corrosion resistance at high temperature. For these reasons, zircaloy-4 is used as a material of cladding fuel rod of nuclear reactors. In this environment, it is submitted to different severe conditions of temperature and pressure. The objective of this work is to study the oxidation kinetics of zircaloy-4 in air by the X-ray diffraction technique. The experiments were realized in a “HTK1200” furnace installed as a sample holder in the diffractometer at different temperatures; 25°C, 350°C, 500°C, 830°C and 1000°C. The results show that the monoclinic and the tetragonal phases are formed at 350°C temperature. The volume fraction of these phases increased with the temperature until 1000°C where the α phase disappears completely. For simulating the case of loss-of-coolant-accident (LOCA), we have done x-ray diffraction of Zry-4 samples water quenched at 1050°C with different ageing times at this temperature. At 10 seconds and more, there is an important evolution of monoclinic and tetragonal zirconias, which leads to the degradation of zircaloy-4 properties.

Deployment Challenges of Offshore Renewable Energy Systems for Sustainability in Developing Countries  [PDF]
Arif Sari, Ali Karaduman, Altay Firat
Journal of Geographic Information System (JGIS) , 2015, DOI: 10.4236/jgis.2015.75037
Abstract: This research aims to expose deployment challenges of offshore renewable energy systems in developing countries. The investigation of the deployment model covers climate conditions, economic conditions, necessary infrastructure services and wind power by considering the case of Cyprus Island which is one of the Small Island Developing States (SIDS) countries. The convenience of Offshore Energy Systems to the territory and their systematic proper work is an important issue. Because of that, the setting up of Offshore Wind Energy Tribunes in Cyprus, the planning process, structuring of cost values and necessary resources, the investigation of the geographic conditions for obtaining the energy flow and assessment of these conditions for Offshore Wind Tribunes are the prime objectives of this study. The orientation period and the applicable qualifications of the offshore energy systems were evaluated on the basis of the world wide references. The study is concluded by the estimation of the advantages and disadvantages of the system for Cyprus.
A Systematic Review of the Extent, Nature and Likely Causes of Preventable Adverse Events Arising From Hospital Care
A Akbari Sari,L Doshmangir,T Sheldon
Iranian Journal of Public Health , 2010,
Abstract: "nBackground: Understanding the nature and causes of medical adverse events may help their prevention. This system-atic re-view explores the types, risk factors, and likely causes of preventable adverse events in the hospital sector."nMethods: MEDLINE (1970-2008), EMBASE, CINAHL (1970-2005) and the reference lists were used to identify the stud-ies and a structured narrative method used to synthesise the data."nResults: Operative adverse events were more common but less preventable and diagnostic adverse events less common but more preventable than other adverse events. Preventable adverse events were often associated with more than one con-tribu-tory factor. The majority of adverse events were linked to individual human error, and a significant proportion of these caused serious patient harm. Equipment failure was involved in a small proportion of adverse events and rarely caused pa-tient harm. The proportion of system failures varied widely ranging from 3% to 85% depending on the data collec-tion and classifi-cation methods used."nConclusion: Operative adverse events are more common but less preventable than diagnostic adverse events. Adverse events are usually associated with more than one contributory factor, the majority are linked to individual human error, and a proportion of these with system failure.
第1页/共28744条
每页显示 条


Home
Copyright © 2008-2020 Open Access Library. All rights reserved.